中文摘要：

目的探讨蒙特利尔认知评估量表（MoCA）中文北京版用于帕金森病（PD）认知评估的可行性。方法分别用MoCA和简易智能状态检查量表（MMSE）对78例PD患者进行认知功能评估，分析评估结果。结果PD患者MoCA与MMSE评分分别为（23．7±3．8）分和（27．7±2．3）分，MoCA评分明显低于MMSE，差异有统计学意义（P〈0．05）；Pearson相关分析显示，MoCA与MMSE总分显著相关（r=0．89，P〈0．05）。在MMSE评定认知功能正常的患者中有50．7％MoCA评定有认知障碍。19例MMSE评分为30分患者的平均MoCA评分为（27．1±1．63）分，其中18例MoCA评分〈30分。MoCA延迟回忆下降发生率明显高于MMSE记忆和回忆能力下降发生率。结论MoCA与MMSE总分上有较好的相关性，MoCA用作PD认知筛查时敏感性高于MMSE，较MMSE更适合用于PD患者的认知障碍筛查。

英文摘要：

Objective To investigate the feasibility of application of Montreal Cognitive Assessment Scale（MoCA） Chinese version to the assessment of global cognition in Parkinson＇s disease （PD）. Methods Seventy-eight PD patients were included. Their cognitive functions were assessed with MoCA and Mini-Mental State Examination（MMSE） and the results were analyzed and compared. Results Mean MoCA and MMSE scores standard deviation were 23.7±3.8 and 27. 7±2.3 respectively. MoCA scores were significantly lower than MMSE scores （P 〈 0.05） and there was a high correlation between the MMSE and the MoCA sores by Pearson correlation tests （r = 0.89,P 〈 0.05）. 50.7% of the PD patients with ＇normal＇ global cognition according to MMSE had cognitive impairment by MoCA. Nineteen cases with MMSE score 30 points had an average score（27.1 ± 1.63） points by MoCA,including 18 cases with MoCA score〈30 points. Conclusion MoCA and MMSE scores have a good correlation. The MoCA has higher sensitivity than the MMSE for cognitive assessment in PD patients. The MoCA is more suitable than the MMSE as a cognitive screening tool for PD patients.