中文摘要：

【目的】研究精氨酸对妊娠环江香猪胎儿生长发育的影响。【方法】试验选取体重35—40 kg的环江后备母猪10头,单栏饲养,每栏1头。配种15 d后,随机分为2组,每组5头。试验组在基础日粮中添加0.83%L-精氨酸,对照组添加1.71%L-丙氨酸（等氮对照）。配种第45天,称取母猪体重,颈动脉放血处死母猪,收集血液,肝素抗凝,离心分离血浆;解剖母猪,记录胎儿数量、重量和存活率,采集羊水、尿囊液和胎盘,-20℃保存,用于实验室分析。【结果】结果表明,精氨酸组与丙氨酸组相比,胎儿平均个体重和黄体数分别提高14.4%（P〈0.05）和6.0%（P〉0.05）,胎盘粗脂肪含量降低14.7%（P〈0.05）,羊水和尿囊液中精氨酸的浓度分别提高65.0%和79.1%（P〈0.05）,尿囊液中赖氨酸浓度降低28.3%（P〈0.05）;血浆和尿囊液中NO的含量分别提高22.9%和66.3%（P〈0.05）,胎盘中总NO合酶、诱导型NO合酶和结构型NO合酶的活性分别提高75.5%、61.7%和84.5%（P〈0.05）。【结论】提示精氨酸通过促进胎盘一氧化氮的生成促进妊娠母猪早期胎儿的生长发育。

英文摘要：

【Objective】The present study was conducted to investigate the effects of arginine（Arg） on growth and development of fetus in Huanjiang mini-pigs.【Method】Ten first-parity female Huanjiang mini-pigs with a live body weight（BW） of 35-40 kg were chosen in this study and raised in ten pens of one pig in each.After 15 days of service,the animals were randomly assigned into two groups（5 pigs per group）,representing supplementation of 1.71% L-alanine（iso-nitrogenous control） or 0.83% L-Arg.After 45 days of service,the sows were weighted and killed by bloodletting of carotid artery.Blood samples were collected into heparin-coated tubes and the plasma were got by centrifugation.The number,BW,survival rate of fetus were observed,and the plasma,amniotic fluid,allantonic fluid and placenta were collected for analysis.【Result】Results showed that the average BW of fetus and corpus luteum number from sow fed Arg-supplemented diet were 14.4%（P0.05） and 6.0%（P0.05） higher,while the content of crude fat in placenta was 14.7% lower（P0.05） than the alanine-supplemented diet group.Dietary addition of Arg increased（P0.05） Arg concentration in amniotic fluid by 65.0% and allantonic fluid by 79.1%,while decreased（P0.05） lysine concentration in allantonic fluid by 28.3%.The concentrations of nitric oxide（NO） in plasma and allantonic fluid in sow fed with Arg-supplemented diet increased（P0.05） by 22.9% and 66.3%,respectively,the activities of total NO synthetase increased by 75.5%,inducible NO synthetase increased by 61.7% and constitutive NO synthetase increased by 84.5% in placenta compared with the control group.【Conclusion】These findings suggested that Arg plays an important role in increasing growth and development of fetus by stimulating NO production of placenta during early pregnancy in sow.