中文摘要：

本文以雄性罗斯肉鸡为材料，探讨饲粮添加不同蛋氨酸源：蛋氨酸（DLM）、蛋氨酸羟基类似物（HMTBA）和蛋氨酸羟基类似物钙盐（HMTB-Ca）对肉鸡骨骼性能和基因表达的影响。结果表明，HMTBA和HMTB--Ca能提高肉鸡终体重、日增重、血液GSH／GSSG比值、抗氧化酶（CAT）水平、总抗氧化能力（T—AOC）、骨骼长度、重量、骨骼指数（p〈O．05）。不同蛋氨酸源对肉仔鸡采食量、料重比和灰分含量影响不显著（P〉0．05），HMTBA组骨生长分化因子-5（GDF-5）表达量显著上升（声〈0．05）。HMTB-Ca显著提高骨骼强度、钙磷含量，下调金属基质蛋白酶-2（MMP-2）、金属基质蛋白酶-9（MMP-9）的表达水平（p〈0．05）。由此可知，采食蛋氨酸羟基类似物及其钙盐饲粮，可提高肉鸡体增重，改善血液氧化还原状态，改善骨骼生长发育，其中HMT昏Ca对骨骼作用更显著。

英文摘要：

The purpose of this study is to investigate the effects of diets supplemented with three different methionine sources DL-Met（DLM）, 2-hydroxy-4-（methythio） butanoic acid （HMTBA） and methionine hydroxy analog-casalt （HMTB-Ca） on bone development and gene expression of broiler chicken. The results showd that, HMTBA HMTB-Ca significantly improved broiler daily weight gain, plasma GSH/GSSG ratio, CAT levels, T-AOC levels, bone length and weight, bone index （p〈0.05）. Examination of daily feed intake, feed efficiency and ash revealed no difference amongst dietary treatments（p〈0.05）, HMTBA significantly increased growth differentiation factor-5 expression levels （p〈0.05） while H MTB-Ca significantly improved bone strength, calcium and phosphorus, and significantly decreased metal matrix metalloproteinase-2, metal matrix metalloproteinase-9 expression levels（p〈0.05）. In conclusion, broilers fed with methionine hydroxy analogue could increase daily weight gain and plasma antioxidant levels, improve bone growth and development especially when HMTB-Ca was fed.