创伤后应激障碍(PTSD)是当机体遭受生命威胁或者强烈精神创伤后发生的疾病。近年来研究发现,一氧化氮可能通过损伤海马神经元、参与创伤记忆的形成和影响海马神经元再生参与PTSD的发生,该文就此进行综述。
Posttraumatic stress disorder(PTSD) is a psychiatric condition that can occur in anyone who has experienced a lifethreatening or violent event.Because of the prominent role in hippocampal damage,neurogenesis and trauma-related memories,nitric oxide(NO) may have an important role in the pathology of PTSD.This article reviews current understanding on the relationship between NO and PTSD.