目的:探讨陈渭良伤科油治疗肌内注射致硬结的临床效果。方法:将120例肌内注射致硬结患者随机分为实验组和对照组各60例,对照组采用50%硫酸镁湿敷,实验组采用陈渭良伤科油治疗,比较两组治疗效果。结果:两组用药第10天与用药前疼痛程度、肿胀程度差值及用药第2天皮肤温度差值比较差异有统计学意义(P〈0.05)。两组不同时间测评硬结面积比较,重复测量方差分析结果显示分组因素间比较差异有统计学意义(P〈0.01),时间因素间比较差异有统计学意义(P〈0.01),分组因素与时间因素具有交互作用(P〈0.01),需进行因素单独效应分析;固定时间因素,两组用药后硬结面积比较差异有统计学意义(P〈0.01)。两组总体疗效、硬结消退时间比较差异有统计学意义(P〈0.05)。结论:陈渭良伤科油可有效消散肌内注射药物所致硬结。
Objective:To investigate the clinical effect of Chenweiliang Shangke You( externally use d oil for burn and traumatic injury) in the treatment of induration induced by intramuscular injection. Methods:120 patients with induration were randomly divided into the ex-perimental group and the control group(60 cases in each group). The treatment of wet compress with 50% Magnesium sulfate was taken in the control group;the patients in the experimental group were treated with Chenweiliang Shangke You. The therapeutic effect was compared between the two groups. Results:The differences in the comparison of the degree of pain and swelling and the skin temperature were statis-tically significant between the two groups on the 10th day of treatment and before treatment(P〈0. 05);the comparison of induration area measured in different time and the grouping factors according to ANOVA results was significantly different between the two groups(P〈0. 01);the difference between the time factors was statistically significant(P〈0. 01);the interaction was found betwen the grouping factors and time factors(P〈0. 01);the differences in the comparison of the fixed time factors and the induration area after treatment were statisti-cally significant between the two groups(P〈0. 01);the comparison of the overall curative effect and the regression time of induration was significantly different between the two groups(P〈0. 05). Conclusion:Chenweiliang Shangke You can effectively dissipate the induration induced by intramuscular injection.