中文摘要：

目的观察益气活络方对早期糖尿病肾病患者的临床疗效。方法选择气虚血瘀型早期糖尿病肾病患者40例，采用随机对照的方法将患者随机分为治疗组及对照组，每组20例。治疗组患者在基础治疗基础上加用三黄糖肾康颗粒，每日一付。分2次口服；对照组患者在基础治疗基础上给予口服洛汀新治疗，每次10mg，每日1次，疗程8周。完成治疗周期后，对2组患者进行一般体格检查和谷丙转氨酶、血肌酐、尿素氮、空腹及餐后2h血糖、糖化血红蛋白、24h尿微量白蛋白、中医症状疗效指数等检查。结果与治疗前（0周）比较，治疗组和对照组尿微量白蛋白显著降低（P〈0．01）；在治疗第6周及第8周，治疗组症候积分显著低于对照组（P〈0．05）；与治疗前比较，2组患者第4、6、8周的症候积分均显著降低（P〈0．05或0．01）。治疗组患者显效4例，有效8例，无效8例，总有效率60％；对照组患者显效4例，有效9例，无效7例，总有效率65％。结论三黄糖肾康颗粒可有效降低早期糖尿病肾病患者24h尿微量蛋白、症候积分水平，且在治疗第6周就能达到最佳中医疗效，对早期糖尿病肾病患者有较理想的防治作用。

英文摘要：

Objective To observe the clinical efficacy of supplementing qi and activating blood circulation prescription in patients with ear- ly type 2 diabetic nephropathy. Methods A total of 40 patients of blood deficiency type with early diabetic nephropathy were selected, and randomly divided into traditional Chinese medicine treatment group and western medicine control group for 20 cases each according to the method of randomly contrast. On the basis of foundation treatment, Chinese medicine treatment group patients received San Huang Tang Shen Kang Particles （daily administration, two times orally ）. On the basis of foundation treatment, western medicine control group patients were giv- en lotensin oral treatment, 10 mg each time, once per day, course of 8 weeks. After completion of treatment, both of two groups of patients re- ceived general medical examination, cereal third transaminase （ALT）, serum creatinine （Scr）, urea nitrogen （BUN）, fasting and postprandial 2 hours blood glucose, glycosylated hemoglobin, 24 h urine trace albumin （U-mAlb）, TCM symptoms curative effect index were determined. Results Comparing with those before treatment （0 weeks）, urine trace albumin was significantly reduced in both Chinese medicine treat- ment group and western medicine control group （P 〈 0.01 ）. After 6 weeks and 8 weeks treatment, TCM syndrome integral was significantly lower in Chinese medicine treatment group than western medicine control group （ P 〈 0.05 ）. Compared with before treatment, symptom scores were significantly lower （P 〈 0.05 or P 〈 0.01 ） at 4,6,8 weeks in both groups with statistical significance. In Chinese medicine treatment group, there were 4 patients of markedly effective, 8 patients of effective, 8 of non-effective, and the total effective rate was 60%. In western medicine control group there were 4 patients of markedly effective, 9 patients of effective, 7 of non-effective, with the total effective rate was 65%. Conclusion San Huang Tang Shen Kang particles c