中文摘要：

目的研究碘化N-正丁基氟哌啶醇对抗BaCl2引起心律失常的作用。方法采用氯化钡诱导的心律失常动物模型，观察碘化N-正丁基氟哌啶醇对抗BaCl2引起心律失常的作用。结果碘化N-正丁基氟哌啶醇（0.5、1、2、4mg／kg）可剂量依赖的减少氯化钡诱发心律失常的发生率，缩短心律失常的持续时间。结论碘化N-正丁基氟哌啶醇具有明显的对抗BaCl2引起心律失常的作用。

英文摘要：

Objective To investigate the effects of N-n-butyl haloperidol iodide （ abbreviated for F2 ） on experimental arrhythmias induced by barium chloride（BaCl2 ）. Methods Arrhythmic models induced by BaCl2 in rats were used to observe the effects of F2 on experimental arrhythmias. Results F2 （0.5, 1, 2, 4 mg/kg） decreased the incidence rate of arrhythmias and shortened the duration of arrhythmias induced by BaCl2 in a concentration dependent manner. Conclusion F2 has significant antiarrhythmic effects on BaCl2- induced arrhythmias.