中文摘要：

目的比较35岁及以上患者接受不同助孕方式后的妊娠结局。方法回顾性分析同济医院妇产科2009年6月至2015年3月进行宫腔内人工授精（IUI）和体外受精-胚胎移植（IVF-ET）的1 403例患者的临床资料,比较、分析不同助孕方式对35岁及以上患者妊娠结果的影响,以及≥35岁和〈35岁患者的妊娠结局。结果在IUI组,用克罗米芬和来曲唑的患者之间妊娠结局无明显差异。IVF-ET组患者的临床妊娠率显著高于IUI组。无论选择何种助孕方式,35岁及以上患者妊娠结局均明显低于35岁以下患者。结论对35岁及以上患者而言,IVF-ET比IUI更加有效。同时,选择在35岁及之前生育是非常必要的。

英文摘要：

Objective To evaluate the pregnancy outcomes of patients who were over 35 years old and received different assisted reproductive treatments.Methods Clinical data of 1 403 patients who underwent intrauterine insemination（IUI）or in vitro fertilization-embryo transfer（IVF-ET）in the Department of Gynecology and Obstetrics of Tongji Hospital were retrospectively analyzed.The effect of IUI and IVF-ET on the pregnancy outcomes of patients aged ≥35 years was analyzed.The pregnancy outcomes were compared between women ≥35 years and35 years.Results In patients undergoing IUI,the results of women taking clomiphene were similar those taking letrozole.Women undergoing IVF-ET had better results than those undergoing IUI.Additionally,women aged≥35 years had significantly lower pregnancy rates than those35 years old irrespective of the assisted treatments used.Conclusion IVF-ET relative to IUI is more effective for infertility women aged more than 35 years old.It＇s essential for women to give birth before 35 years old.