中文摘要：

挤出滚圆法是国内外应用最广泛的一种微丸制备方法.制备过程中,处方因素（如干粉和软材的理化性质等）和工艺参数与所得微丸的质量有显著的相关性,其中软材的物理性质是影响微丸成型性的重要因素.本文总结并阐述了国内外关于软材物理性质的表征方法、影响软材物理性质的因素及其与微丸成型性之间相关关系的研究概况.

英文摘要：

Extrusion-spheronization process has become one of the mostly used methods for the preparation of pellets at home and abroad. The formulation parameters （such as physicochemical properties of dry powders and wet mass） and the process parameters are associated mainly with the quality of pellets, and physical properties of wet mass have been found to have significant influence on formability of the resultant pellets. Therefore, the physical properties and characterization of wet mass as well as the association with the formability of pellets are reviewed on the basis of literatures at home and abroad.