目的观察清瘟败毒饮对脓毒症邪陷肺卫证患者急性生理与慢性健康(APACHEⅡ)评分、C反应蛋白(CRP)、血白细胞计数(WBC)、中医证候评分、血糖与体温显效率的影响。方法将患者50例按随机数字表法随机分为西医组与中西医组各25例。西医组采用西医常规治疗,中西医组在西医组基础上加予中药治疗,检测治疗前后3 d、7 d观察各项目变化。结果治疗后两组患者APACHEⅡ评分、CRP、WBC、中医证候评分、退热时间均明显改善,中西医组明显优于西医组(P〈0.05)。结论清瘟败毒饮治疗脓毒症邪陷肺卫证无明显器官衰竭表现,能显著改善患者临床症状及缩短病程。
Objective: To investigate the clinical effects of Qingwen Baidu Decoction on Fengwen Syndrome in patients with Sepsis. Methods: Cases were randomly divided into the western medicine group and the Chinese and western medicine group. All 50 cases were treated with routine modality and 25 cases of the Chinese and western medicine group were treated with additional TCM treatments. Both groups were rated by APACHE Ⅱ score, CRP, WBC, TCM syndrome evaluation before and after 3-days,7-days of treatments. Results: APACHE Ⅱ score, CRP, WBC, TCM syndrome evaluation were lower in the Chinese and western medicine group than those in the western medicine group,with significant differences. Conclusion: Compared with the western medicine group,clinical effects of Qingwen Baidu Decoction on pathogen-invading-lung syndrome in patients with sepsis were significantly different in the Chinese and western medicine group without obvious organ failure and can shorten the course of disease.