中文摘要：

罗丹宁复合份菁染料是一类应用广泛的有机功能染料。其具有摩尔吸光系数高、光谱响应范围广以及荧光量子产率高等特性。但其在生物医学领域报道中可直接应用的染料种类太少。本文简述了近年来罗丹宁复合份菁染料在一些生物医学领域方面的应用。分析说明罗丹宁复合份菁染料组分单一,结构明确,性质稳定,其在抗疟疾和抗肿瘤活性检测中显现出一定活性,且可作为潜在的光敏剂应用于光动力疗法中,同时在体外细胞成像和活体成像中也显示出了一定的应用价值等。说明了罗丹宁复合份菁染料在生物医学领域具有很好的应用潜力,应进一步开发新型结构且性能优良的份菁染料以及深入挖掘其在生物医学领域的应用价值。

英文摘要：

Rhodanine compound cyanine dye is a kind of widely used organic dyes that have high molar absorption coefficient,wide range of spectral response,and the high quantity of fluorescent rate. However,there are few reports on the direct applications in the field of biomedical dye types. This paper discussed the latest biomedical applications of rhodanine compound of cyanine dyes. Because of single component,well defined structure,and the stable properties,rhodanine compound cyanine dye has been applied to fight malaria,antitumor,photodynamic therapy,cell imaging,etc. It showed a certain activity in malaria and antitumor activity detection,and can be used as potential photosensitizer for light photodynamic therapy,and in vitro cell imaging. The rhodanine compound of cyanine dyes have good potential applications in biomedical field. The development of the novel structure and excellent performance of cyanine dyes will extend its application in the field of biomedical.