中文摘要：

调查 Xuebijing (XBJ ) 注射的药品效果的目的，中国专利药，在严重肺的殴打(PC ) 上。有 PC 的六十三个病人独自加 XBJ 注射(n=33 ) 或常规治疗被使随机化到常规治疗的方法(n=30 ) 。，在在 corticosteroid 的组差别之间，治疗，有免疫力的规定治疗， hemofiltration，注入体积，输送体积和抗菌素时期被测量是特别护理单位(ICU ) 空闲的时间，通风时间， 28 天的死亡率和联系通风的肺病(VAP ) 的发生。procalcitonin (%) 的浆液集中，肿瘤坏死因素 --(TNF-) ， interleukin (IL )-6, 和 IL-10，白血房间(白血球) 计数和人的白血球抗原 DR/CD14+(HLA-DR/CD14+) 的百分比外部血 mononuclear 房间被比较。通风的标记被血气体分析和通风机参数决定。结果白血球计数和 % ， TNF- ， IL-6 和 IL-10 的浆液集中更快速显著地被减少，并且 CD14+ 百分比更早显著地被增加，在比在控制组的 XBJ 组(P < 0.05 各个) 。通风和氧化索引的水平比在控制组在 XBJ 更早被改善(P < 0.05 ) 。XBJ 处理显著地减少了 ICU 停留时间，通风时间和 VAP 的发生(P < 0.05 各个) ，但是没在 28 天的死亡率上有效果(P > 0.05 ) 。结论 XBJ 治疗能弄短 ICU 免费并且通风时间和还原剂 VAP 的发生，在有严重 PC 的病人的改善结果。XBJ 可以由调整发炎和免疫行动，减轻损伤导致的全身的煽动性的反应症候群。

英文摘要：

OBJECTIVE： To investigate the curative effects of Xuebijing （XBJ） injection, a Chinese patent medi- cine, on severe pulmonary contusion （PC）. METHODS： Sixty-three patients with PC were ran- domized to conventional therapy plus XBJ injec- tion （n=33） or conventional therapy alone （n=30）. Between groups differences in corticosteroid treat- ment, immune regulation therapy, hemofiltration, infusion volume, transfusion volume and antibiotic period were measured, as were intensive care unit（ICU）-free time, ventilation time, 28-day mortality rate and incidence of ventilation-associated pneu- monia （VAP）. Serum concentrations of procalcito- nin （PCT）, tumor necrosis factor-a （TNF-a）, interleu- kin （IL）-6, and 11_-10, white blood cell （WBC） counts and percentages of human leukocyte antigen DR/ CD14＋ （HLA-DR/CD14＋） peripheral blood mononu- clear cells were compared. Markers of ventilation were determined by blood gas analysis and ventila- tor parameters. RESULTS： WBC counts and serum concentrations of PCT, TNF-a, 11.-6 and IL-10 were reduced signifi- cantly more quickly, and CD14＋ percentage was in- creased significantly earlier, in the XBJ group than in the control group （P〈0.05 each）. The level of ven- tilation and oxygenation index were ameliorated earlier in the XBJ than in the control group （P〈 0.05）. XBJ treatment significantly reduced ICU-free time, ventilation time and incidence of VAP （P〈0.05 each）, but had no effect on 28-day mortality rate （P〉0.05）. CONCLUSION： XBJ treatment can shorten ICU-free and ventilation times and reduce the incidence of VAP, improving outcomes in patients with severe PC. XBJ may act by regulating inflammation and im- munity, alleviating systemic inflammatory response syndrome induced by trauma.