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肝细胞微囊化技术理论进展与临床应用
  • 期刊名称：中国组织工程研究与临床康复, 2010,14(3):549-551
  • 时间：0
  • 分类：R318[医药卫生—生物医学工程;医药卫生—基础医学]
  • 作者机构：[1]上海交通大学医学院瑞金医院,上海市200025
  • 相关基金：国家“十一五”高新技术研究发展计划-“863”项目（2008AA02Z417）; 上海市科委自然科学基金（07ZR14076）; 国家自然科学基金重点项目（20434030）; 国家自然科学基金（30672043 30772105 20074031 30801107）; 上海市教委科研创新项目（09YZ84）~~
  • 相关项目：新型微粒生物人工胰反应器构建的研究
关键词： 微囊, 生物型人工肝, 肝细胞移植, 肝细胞, 综述文献
中文摘要：

肝细胞分离技术日趋成熟,肝细胞移植成为较热门的研究领域,但供体短缺和免疫排斥反应,制约了其广泛应用。肝细胞微囊化有助于为肝细胞移植的推广应用提供大量的具有高度活性和良好功能的肝细胞。文章就肝细胞微囊化技术及其应用进展进行综述,为肝细胞大规模、高活性体外培养及长期冻存提供了新的途径。

英文摘要：

With the development of cell separation technique,hepatocyte transplantation becomes a hot topic;however,the application is limited by donor deficiency and immunological rejection.Microencapsulated hepatocytes contribute to the promotion and application for liver cell transplantation,for which provide a large amount of high activity and good function of liver cells.In this paper,liver cell microencapsulation technology and its progress in applications were reviewed,providing prospective way for large-scale and high-active culture in vitro and long-term cryopreservation.

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微囊化细胞的低温保存.
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海藻酸钠/壳聚糖微囊冻存的低温显微实验
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微囊化细胞的低温保存
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肝细胞体外培养技术的研究与进展
肝细胞微囊化技术理论进展与临床应用.
A microscopic study of the alginate/chitosan/alginate microcapsules cryopreservation.
微囊胰岛移植的实验研究进展.
肝细胞移植的临床应用.
肝细胞球形聚集体培养研究进.
Biocompatibility of human hepatocyte/microporous polypropylene hybridization.
肝细胞体外培养技术的研究与进展.
微载体及其在肝细胞培养中的研究进展.
接枝改性微孔聚丙烯超滤膜的生物相容性评价.
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微载体培养技术的研究与进展.
微囊化细胞冻存的研究进展.
改良胶原酶经腹主动脉灌注消化法分离大鼠肝细胞.
Establishment of L02 human hepatocyte compatible polypropylene interface.
海藻酸钠/壳聚糖微囊冻存的低温显微实验.
海藻酸钠/壳聚糖微囊冻存的低温显微实验
微载体培养技术的研究与进展
微囊化细胞的低温保存
人肝细胞臌孔聚丙烯杂化界面的生物相容性
壳聚糖球形多孔微载体支持下人肝细胞L-02的高浓度细胞培养
球形多孔微载体支持下高密度培养人肝细胞L-02的定时形态变化
Preliminary Characteristic of Alginate, Heparin-Chitosan-Alginate, Heparin Microencapsulated Hepatocytes System
肝细胞移植的临床应用
Preparation and characterization of chitosan porous microcarriers for hepatocyte culture
胰腺癌动物模型的研究进展