位置：成果数据库 > 期刊 > 期刊详情页
Progress in fabricating arrays of soft spherical vessels on mesoscale with spatial control
  • 时间：0
  • 分类：Q4[生物学—生理学]
  • 作者机构：[1]Key Laboratory of Macromolecular Synthesis and Functionalization, Ministry of Education, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
  • 相关基金：Supported by the Postdoc Foundation of Zhejiang Province, the National Natural Science Foundation of China （Grant Nos. 20434030, 20774084）, the National Basic Research Program of China （Grant No. 2005CB623902） and the National Natural Science Funds for Distinguished Young Scholars of China （Grant No. 50425311）
  • 相关项目：智能微胶囊的制备、特异识别与填充释放
关键词： 泡状体, 脂质体, 微胶囊, 空间控制, vesicles, liposomes, microcapsules, microarray, self-assembly, soft lithography
中文摘要：

象一些， polymerized 泡和聚合电解质囊可以在简历分析，察觉到的简历，和组合化学发现多样的应用的 lipo 那样的球形的像容器的胶体的 Microarrays 为他们在包含象药那样的化学种类的能力，简历分子，探针，聚合物和 nanoparticles。这评论为制作各种各样的空胶体的微数组在方法上报导进展。相关策略详细被描述，包括象寡核 酸杂交， receptor-ligand 绑定，共有原子价联合和静电的相互作用那样的 patterning 技术，表面修正方法，和拴住的途径。用作传感器芯片，微搬运人和微反应堆的这些数组的功能的初步的开发也被总结。

英文摘要：

Microarrays of spherical vessel-like colloids such as liposomes, polymerized vesicles and polyelectrolyte capsules may find diverse applications in bioanalysis, biosensing, and combinatorial chemistry, for their capabilities in encapsulating chemical species such as drugs, biomolecules, probes, polymers and nanoparticles. This review reports the advances on methods for fabricating microarrays of the various hollow colloids. Related strategies are described in detail, including patterning techniques, surface modification methods, and tethering approaches such as oligonucleotide hybridization, receptor-ligand binding, covalent coupling and electrostatic interaction. The preliminary developments of functionalities of these arrays serving as sensor chips, microcarriers and microreactors are summarized as well.

同期刊论文项目
生物医用高分子材料
期刊论文 94 会议论文 70 获奖 2 著作 2
智能微胶囊的制备、特异识别与填充释放
期刊论文 73 会议论文 35 获奖 2 著作 1
层状组装聚合物超薄膜的压缩与图案化生物功能材料制备
期刊论文 7
同项目期刊论文
不同表面性质聚电解质多层膜的制备及蛋白质吸附和血液相容性能
表面温敏聚合物刷的原子力显微镜和石英晶体微天平研究
溶剂辅助聚合物微成型
Covalently immobilized gelatin gradients within three-dimensional porous scaffolds
Solvent-assisted polymer micro-molding
聚合物纳米粒子的结构和性能对胞吞和细胞功能的影响
Poly(lactic acid) scaffold fabricated by gelatin particle leaching has good biocompatibility for cho
Fabrication and physical and biological properties of fibrin gel derived from human plasma
Fabrication of bovine serum albumin microcapsules by desolvation and destroyable crosslinking
Surface modification and property analysis of biomedical polymers used for tissue engineering
Chitosan–hyaluronic acid hybrid film as a novel wound dressing: in vitro and in vivo studies
Specially elaborated thermally induced phase separation to fabricate poly(L-lactic acid) scaffolds w
软骨细胞在聚乳酸支架中的体外生长行为
Surface wettability of compressed polyelectrolyte multilayers
Preparation and properties of an injectable scaffold of poly(lactic-co-glycolic acid) microparticles
层层组装微胶囊的制备及其智能响应与物质包埋释放性能
Loading and release behaviors of compressed polyelectrolyte multilayers for small dye molecules
Enhanced Angiogenesis in Porous Collagen-Chitosan Scaffolds Loaded with Angiogenin
Microscale control over collagen gradient on poly(L-lactide) membrane surface for manipulating chond
Photoinitiating polymerization to prepare biocompatible chitosan hydrogels
In vitro and in vivo biological performance of collagen-chitosan/silicone membrane bilayer dermal eq
Collagen-coated polylactide microspheres as chondrocyte microcarriers
Collagen/chitosan-silicone membrane bilayer scaffold as a dermal equivalent
Preparation of porous polylactide microspheres by emulsion-solvent evaporation based on solution ind
Collagen-coated polylactide microcarriers/chitosan hydrogel composite: Injectable scaffold for carti
Layer-by-layer assembly of biomacromolecules on poly(ethylene terephthalate) films and fiber fabrics
Fabrication of Thermoresponsive Polymer Gradients for Study of Cell Adhesion and Detachment
壳聚糖涂层聚乳酸细胞微载体的制备和性能
聚(二甘氨酸乙酯)磷腈的合成及其生物相容性
Hydrogel-filled polylactide porous scaffolds for cartilage tissue engineering
N,N,N-trimethyl chitosan chloride as a gene vector: synthesis and application
In vitro and in vivo degradability and cytocompatibility of poly(L-lactic acid) scaffold fabricated
Hollow chitosan-alginate multilayer microcapsules as drug delivery vehicle: doxorubicin loading and
Layer-by-layer assembly of chondroitin sulfate and collagen on aminolyzed poly(l-lactic acid) porous
Crosslinked polysaccharide nanocapsules: Preparation and drug release properties
Multilayer Microcapsules as Anti-Cancer Drug Delivery Vehicle: Deposition, Sustained Release, and in
Ibuprofen-loaded nanoparticles prepared by a co-precipitation method and their release properties
Bioactive Thin Film of Acidic Fibroblast Growth Factor Fabricated by Layer-by-Layer Assembly
Printing biomacromolecules on a bovine serum albumin precursor layer
Microstructure and mechanical properties of poly(L-lactide) scaffolds fabricated by gelatin particle
交联聚乳酸中空微球的制备与表征
Charge-Controlled Permeability of Polyelectrolyte Microcapsules.
Thermosensitive poly(allylamine)-g-poly(N-isopropylacrylamide): synthesis, phase separation and part
Surface modification of poly(ethylene terephthalate) via hydrolysis and layer-by-layer assembly of c
胶原/壳聚糖组织再生支架及其在修复皮肤损伤中的应用
Manipulating the Properties of Polyelectrolyte Microcapsules by Glutaraldehyde Cross-Linking,
Chitosan modified poly(l-lactide) microspheres as cell Microcarriers for cartilage tissue engineerin
Cartilage tissue engineering PLLA scaffold with surface immobilized collagen and basic fibroblast gr
The gene transfection efficiency of thermoresponsive N,N,N-trimethyl chitosan chloride-g-poly(N-isop
Gelatin/chitosan/hyaluronan scaffold integrated with PLGA microspheres for cartilage tissue engineer
Poly(ethylene glycol) micro-patterns as environmentally sensitive template for selective or non-sele
通过可控沉积和交联制备蛋白质微胶囊
纳米金掺杂中空微胶囊的制备与表征
溶剂辅助聚合物微成型
Solvent-assisted polymer micro-molding
交联壳聚糖水凝胶填充层状微胶囊的制备与性能
胶原-磺化羧甲基壳聚糖/硅橡胶皮肤再生材料的制备及其对小型猪烫伤创面全层皮肤缺损的修复研究
肝细胞微囊化技术理论进展与临床应用
自组装阿霉素微囊肝动脉灌注对兔VX2肿瘤细胞代谢及凋亡的影响
Polyphosphazene Microcapsules Fabricated through Covalent Assembly
层层组装微胶囊的制备及其智能响应与物质包埋释放性能
交联壳聚糖水凝胶填充层状组装微胶囊的制备与性能
通过可控沉积和交联制备蛋白质微胶囊
纳米金掺杂中空微胶囊的制备与表征
Multilayer microcapsules with tailored structures for bio-related applications
Multilayer poly(ethyleneimine) microcapsules: glutaraldehyde mediated assembly and the influence of
pH-responsive protein microcapsules fabricated via glutaraldehyde mediated covalent layer-by-layer a
Manipulating the properties of coacervated polyelectrolyte microcapsules by chemical crosslinking
原位凝聚法制备聚电解质微胶囊：模板中聚电解质掺杂量对微胶囊结构与性能的影响
Polyelectrolyte coated PLGA nanoparticles: templation and release behavior
Biomimetic modification of chitosan with covalently grafted lactose and blended heparin for improvem
Stepwise interfacial self-assembly of nanoparticles via specific DNA pairing,
Chitosan Nanoparticles for Loading of Toothpaste Actives and Adhesion on Tooth Analogs
Gelatin/chitosan/hyaluronan ternary complex scaffold containing basic fibroblast growth factor for c
The influence of polycaprolactone coating on the internalization and cytotoxicity of gold nanopartic
Incorporation of Basic Fibroblast Growth Factor by a Layer-by-Layer Assembly Technique to Produce Bi
Rings of Hydrogel Fabricated by a Micro-Transfer Technique
Selective removal of particle cores to fabricate manganese carbonate hollow spheres and composite mi
Layered microcapsules for daunorubicin loading and release as well as in vitro and in vivo studies
Covalently crosslinked chitosan hydrogel formed at neutral pH and body temperature
Assembly of multilayer microcapsules on CaCO3 particles from biocompatible polysaccharides
Equilibrium Distribution of Permeants in Polyelectrolyte Microcapsules Filled with Negatively Charge
Influence of assembling pH on the stability of poly(L-glutamic acid) and poly(L-lysine) multilayers
Assembly of polymeric micelles into hollow microcapsules with extraordinary stability against extrem
Stepwise assembly of the same polyelectrolytes using host-guest interaction to obtain microcapsules
Influence of Drying Time of Polyelectrolyte Multilayers on the Compression-Induced Pattern Formation
Preparation and properties of ionically cross-linked chitosan nanoparticles
Direct Covalent Assembly to Fabricate Microcapsules with Ultrathin Walls and High Mechanical Strengt
Template Polymerization to Fabricate Hydrogen-Bonded Poly(acrylic acid)/Poly(vinylpyrrolidone) Hollo
Hollow microcapsules with a complex polyelectrolyte shell structure fabricated by polymerization of
A facile pathway to fabricate microcapsules by in situ polyelectrolyte coacervation on poly(styrene
Polyelectrolyte microcapsules templated on poly(styrene sulfonate)-doped CaCO3 particles for loading
Thermosensitive poly(allylamine)-g-poly(N-isopropylacrylamide) copolymers: Salt-tuned phase separati
In situ coacervated microcapsules with filled polyelectrolytes and charge-controlled permeation for
Chitosan-Mediated Synthesis of Gold Nanoparticles on Patterned Poly(dimethylsiloxane) Surfaces
Compression-Inhibited Pore Formation of Polyelectrolyte Multilayers Containing Weak Polyanions: A Sc
Biologically Driven Assembly of Polyelectrolyte Microcapsule Patterns To Fabricate Microreactor Arra
Polylactide hollow spheres fabricated by interfacial polymerization in an oil-in-water emulsion syst
Stable weak polyelectrolyte microcapsules with pH-responsive permeability
Fabrication of microcapsule arrays on chemically patterned surfaces via covalent linking
海藻酸钠/壳聚糖微囊冻存的低温显微实验
自组装阿霉素微囊对兔肝脏VX2移植瘤治疗的PET/CT评价
Single Polyelectrolyte Microcapsules Fabricated By Glutaraldehyde-Mediated Covalent Layer-By-Layer A
Two-dimensional chemically tunable patterns with cellular structures fabricated via thermal pressing
Stable microcapsules assembled stepwise from weak polyelectrolytes followed by thermal crosslinking
Robust poly(allylamine)-graft-poly(Nisopropylacrylamide) particles prepared by physical crosslinking
Multilayer Capsules with Cell-like Topology: Fabrication and Spontaneous Loading of Various Substanc
Preformed microcapsules for loading and sustained release of ciprofloxacin hydrochloride
微囊化细胞的低温保存
交联壳聚糖水凝胶填充层状微胶囊的制备与性能
Preliminary Characteristic of Alginate, Heparin-Chitosan-Alginate, Heparin Microencapsulated Hepatocytes System