中文摘要：

目的：对南海沿海海藻内生真菌ZJ27次级代谢产物进行研究。方法：采用色谱技术进行分离纯化,结合理化性质和波谱分析技术确定化合物的结构。结果：从真菌ZJ27次级代谢产物中分离得到5个化合物,分别为：核丛青霉素（1）、ochrephilone（2）、6-（（3E,5E）-5,7-二甲基-2-酮基-3,5-壬二烯基）-2,4-二羟基-3-甲基苯甲醛（3）、（2E,4E）-4,6-二甲基-2,4-辛二烯酸（4）、pencolide（5）。结论：化合物1量特别大,达11 g,化合物2也有66 mg,因此本菌经优化培养可望成为药源微生物。

英文摘要：

Objective：To study the secondary metabolites of coastal seaweed endophytic fungi ZJ27.Methods：The compounds were isolated by chromatographic technique.The structures were identified by comprehensive physic-chemical properties and spectral methods.Results：Five compounds were isolated and identified as sclerotiorin（1）,ochrephilone（2）,6-（（3E,5E）-5,7-dimethyl-2-methylenenona-3,5-dienyl）-2,4-dihydroxy-3-methylbenzaldehyde（3）,（2E,4E）-4,6-dimethylocta-2,4-dienoic acid（4）,pencolide（5）.Conclusion：11 g of the compound 1 and 66 mg of the compound 2 were isolated from this fungi indicate that it may develop to be medical source microorganism.