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中文摘要：
1个新的苯并-γ-吡喃酮衍生物，3，5-二羟基-2-甲基-6-（3-甲基-2-丁烯基）苯并-γ-吡喃酮（1），以及1个结构独特的环四肽（2）和3个环二肽，从南海红树林内生真菌ZZF41代谢产物中分离得到。它们的结构通过MS、NMR等波谱分析推导确定。化合物1对人鼻咽癌细胞株KB和人鼻咽癌细胞耐药株KBv200显示了微弱的细胞毒活性（IC50均大于50μg／mL），而2对同样细胞株有细胞毒活性（IC50均小于3．56μg／mL）。
英文摘要：
A new chromone derivative named as 5-dihydroxy-2-methyl-6- （3-methylbut-2- enyl） -4H- chromen-4-one （1）, a novel cyclic tetrapeptide （2） and three cyclic dipeptides were isolated from the mangrove endophytie fungus ZZF41 from the South China Sea. Their structures were characterized by MS, NMR. Compound 1 exhibited weak cytotoxicity towards KB and KBv200 with ICs0values of more 50 μg/mL. Compound 2 showed cytotoxicity towards KB and KBv200 with IC50 values of less 3.56 μg/mL, respectively.
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