中文摘要：

目的：对南海红树林内生真菌BL321次级代谢产物进行研究。方法：采用色谱技术进行分离纯化,理化性质和波谱分析技术确定化合物的结构。结果：从南海红树林内生真菌BL321次级代谢产物中分离并鉴定了5个化合物,分别为：3,4a-dimethyl-2-oxo-2,4,4a,5,6,7-hexahydronaphtho[2,3-b]furan-5-carboxylic acid（1）、松胞素C（2）、松胞素D（3）、19,20-环氧松胞素C（4）、麦角甾醇（5）。结论：化合物1为首次从自然界中分离得到。并且该菌能产生多种强活性松胞素类化合物,因此经优化培养可望成为药源微生物。

英文摘要：

Objective： To study the secondary metabolitws of mangrove endophytic fungus BL321.Methods： The compounds were isolated by chromatographic technique.The structures were identified by comprehensive physico-chemical properties and spectral methods.Results： Five compounds were isolated and identified as 3,4a-dimethyl-2-oxo-2,4,4a,5,6,7-hexahydronaphthofuran-5-carboxylic acid（1）,cytochalasin C（2）,cytochalasin D（3）,19,20-epoxycytochalasin C（4）,ergosterol（5）.Conclusion： Compound 1 is isolated from nature for the first time.Further more,several kinds of strong bioactive compounds were islolate from this fungus indicate that it may develop to be medical source microorganism.