在血管活性肠肽是免疫系统中具有重要免疫调节作用的神经肽。近年的研究表明,血管活性肠肽通过多条途径产生促进Th2细胞应答和抑制Th1细胞增殖,影响B细胞的分化,抑制NK细胞的活性为特点的免疫应答。本文就血管活性肠肽在调节淋巴细胞分化的研究进展作一综述。
Vasoactive intestinal peptide (VIP) is the most important neuropeptide in immune system. The recent researches indicated that VIP enhanced respondence of Th2 cell, inhibited proliferation of Thl cell, impacted differentiation of B cell, and inhibited activity of NK cell through several pathways. This article mainly reviewed the advance on VIP regulating lymphocyte differentiation in recent years.