目的研究吸毒人群的中医病理因素特点。方法对吸毒者和健康者进行对照研究,中医病理因素采用证素辨证方法采集。结果吸毒组肝证素积分频数最高;与健康组相比,吸毒组的五脏病位证素积分值均差异有统计学意义(P〈0.01);吸毒组痰、湿、气滞和阴虚等病性证素积分频数最高;与健康组相比,吸毒组的病性证素积分值均差异有统计学意义(P〈0.01)。结论毒品成瘾形成是多脏腑(肝、肾、脾)功能失调的表现,多属虚实夹杂之证。虚证病性证素主以阴虚为主:实证病性证素主以痰、湿、气滞为主;病位主在肝、肾。
Objective To study the characteristics of pathological factors of TCM of drug users. Methods Case-control study was conducted between the drug addicts and the healthy persons. The pathological factors of TCM of drug addicts were collected by categorical identification in terms of syndrome factor. Results The integral frequency of liver syndrome element of drug group was the highest. Compared with the healthy group, the integral means of Five Viscus disease location syn- drome element of drug addicts showed significant difference (P〈0.01). The syndrome element integral frequency of phlegm, wet and qi stagnation and yin deficiency of drug group were higher. Compared with the healthy group, the integral means of pathological characteristics syndrome element of drug addicts showed significant difference (P〈O.01). Conclusion Drug addiction is the result of function- al disturbance of several viscus (liver, kidney, spleen) and can be largely attributed to the vacuity-re- pletion complex pattern. The main pathological characteristics syndrome element of deficiency pattern is yin deficiency, the main pathological characteristics syndrome element of repletion pattern is phlegm, wet and qi stagnation, the disease location mainly lies in liver and kidney.