中文摘要：

目的：研究吸毒人群血清ACTH、5-羟色胺（5-HT）、β-内啡肽和cAMP水平与健康人群的差异。方法：对吸毒者和健康者进行病例-对照研究,吸毒者诊断标准均符合《中国精神障碍分类与诊断标准》第三版（CCMD-3）。结果：吸毒组与健康组血清cAMP水平存在显著性差异;5-HT、ACTH、β-内啡肽水平在两组间无显著性差异。结论：吸毒人群血清cAMP的含量升高可能是影响情志改变的因素之一。

英文摘要：

Objective：To compare the levels of serum ACTH,5-HT,β-endorphin,cAMP among drug addicts and control subjects.Methods：The cases-control comparison between drug addicts and healthy people was adopted.Diagnosis standards of drug addicts conform to the standards in Chinese Classification of Mental Disorders,CCMD-3.Results：There is a significant difference in cAMP level between drug addict group and healthy group;while no differences in 5-HT,ACTH,β-endorphin between two groups were observed.Conclusion：The increased serum cAMP may be one of the factors that influence the emotion changes in drug addicts.