中文摘要：

目的：探讨围绝经期综合征肝郁病理与雌性激素之间的相关性。方法：采用随机数字表法,选取50例健康妇女作为对照组,150例围绝经期综合征患者作为观察组,采用证素辨证进行肝郁病理改变分析,观察肝郁病理与雌性激素水平之间的关系。结果：围绝经期综合征肝郁积分,观察组明显高于对照组（P〈0.01）;肝郁病理改变分布情况,观察组与对照组有明显差异（P〈0.01）;月经紊乱和绝经的肝郁病理改变,与FSH、LH、FSH/LH呈正相关,与E2呈负相关。结论：肝郁病理是围绝经期综合征的核心病机之一,与FSH、LH、FSH/LH呈正相关,与E2水平变化呈负相关。

英文摘要：

Objective： Study interrelationship of liver depression and estrogen in perimenopausal syndrome. Methods： 150 cases of the perimenopausal syndrome were randomly observed, 50 healthy women as control. Using of syndrome elements differentiation, observed the relationship of liver depression and estrogen level. Results： Liver depression scores of perimenopausal syndrome, the observation groups were significantly heavier than the control group （P〈0.01）. Liver depression pathological change of perimenopausal syndrome, the observation groups were significantly heavier than the control group （P〈0.01）. It was liver depression positively correlated with FSH, LH and FSH/LH, and negatively correlated with E2, in perimenopausal syndrome menstrual disorders and menopausal. Conclusion： Liver depression is one of the cores of pathogenesisa in the perimenopansal syndrome, which is positively correlated with FSH, LH and FSH/LH, and negatively correlated with E2 Levels.