目的探讨围绝经期综合征中医证素辨证规律。方法选择100例围绝经期综合征患者作为观察对象,采用证素辨证及积分方法进行临床观察。结果围绝经期综合征虚证证素阴虚、血虚、阳虚显著高于气虚(P〈0.05,P〈0.01),阴虚、血虚高于阳虚(P〈0.05);围绝经期综合征实证证素肝郁、气滞、热积分显著高于湿、痰(P〈0.05,P〈0.01);围绝经期综合征病住证素以肝、肾、脾积分显著高于肺、心(P〈0.01)。结论围绝经期综合征虚证证素主要以阴虚、血虚、阳虚为主;实证证素主要以肝郁、气滞、热为主;病位证素主要在肝、肾、脾,属虚实夹杂之证。
Objective To explore the rules of TCM syndrome elements of perimenopausal syndrome (PMS). Methods 100 PMS patients were selected as the subjects and observed by syndrome elements differentiation and integral methods. Results In asthenia syndrome of PMS, the integrals of syndrome elements of Yin deficiency, blood deficiency and Yang deficiency were significantly higher than that of Qi deficiency respectively (P〈0.05, P〈0.01), and the integrals of syndrome elements of Yin deficiency and blood deficiency were significantly higher than that of Yang deficiency respectively (P〈0.05). In sthenia syndrome of PMS, the integrals of syndrome elements of liver depression, Qi stagnation and heat were significantly higher than that of dampness, phlegm respectively (P〈0.05, P〈0.01). The syndrome elements integrals of liver, kidney and spleen were significantly higher than that of lung, heart respectively (P〈0.01). Conclusion PMS is the excessive and deficiency syndrome, and the main syndromes are Yin deficiency, blood deficiency and Yang deficiency in asthenia syndrome; the main syndromes are liver depression, Qi stagnation and heat in sthenia syndrome; the main syndrome elements of disease location are in liver, kidney, spleen.