中文摘要：

银屑病是一种常见的慢性复发性炎症性皮肤病,发病机制复杂,病理表现为角质细胞异常增生分化、淋巴细胞浸润、微血管扩张等。趋化因子是一类由白细胞和某些基质细胞分泌的具有趋化炎症反应细胞定向迁移的作用的细胞因子,根据结构不同可分为4类,而β趋化因子作为其中一类已被发现通过与其特异受体结合,从而诱导免疫细胞迁徙进入皮损,参与了银屑病的多个发病环节。

英文摘要：

Psorlasis is a common chronic relapsing inflammatory skin disease, with complex pathogene- sis, and pathological manifestations of abnormal proliferation of keratinecyte differentiation,infiltration of lymphocytes, microvascular expansion etc, Chemokines are a class of white blood cells and cytokines secreted by some stromal cells with cell migration directing function, and can be divided into four categories according to the structure, while the β chemokine as one class has been discovered to be binding to its specific receptors, thereby inducing the migration of immune cells into the skin lesions, and participate in several processes of the pathogenesis of psoriasis.