中文摘要：

人参皂苷-Rh2诱导肿瘤细胞凋亡机制复杂,且不同机制间相互联系。它主要通过调节细胞周期蛋白依赖性激酶复合物特异性信号传递引发细胞周期阻滞诱导细胞凋亡,或通过调控细胞信号转导通路,如ROS、Ca2＋、PKC、JNK介导的线粒体信号通路和TRAIL-R1（DR4）介导的死亡受体信号通路等诱导肿瘤细胞凋亡。

英文摘要：

Ginsenoside-Rh2-induced tumor apoptosis signaling pathways are complicated and always involved in cross-talking among different pathways. It can cause tumor apoptosis by inducing cell cycle arrest or regulating ROS, Ca2＋, PKC, or JNK-mediated cell signaling pathways and TRAIL-R1（DR4）-mediated death receptor pathways.