中文摘要：

目前流行病学研究发现,植物雌激素在疾病的预防和治疗方面发挥重要作用,对心血管疾病、围绝经期综合症、乳腺癌、子宫内膜癌、结肠癌等肿瘤具有预防和抑制作用.体内雌激素分泌紊乱或雌激素受体代谢失常可诱发多种相关疾病或加速疾病进程,长期摄入植物雌激素可能对子宫内膜、乳腺以及男性生殖系统产生不良影响.所以植物雌激素的药理学作用仍需要进行研究,对其不良反应作用机制等需要进一步探讨.介绍了有关植物雌激素的药理学作用及其作用机制的研究.

英文摘要：

At present epidemiological studies found that phytoestrogen plays an important role in the prevention and the occurrence of cancer,and inhibit the growth and proliferation of tumor cells,including mammary cancer,prostate cancer,endometrial carcinoma,ovarian cancer,colon carcinoma,leukemia,and hepatic carcinoma and gastric cancer. In vivo estrogen secretion disorder or estrogen receptor metabolism disorders often can induce a variety of related diseases or accelerate the process of disease,long- term intake of phytoestrogens may have on endometrial,breast,and negative effects on the male reproductive system. The pharmacological effects of phytoestrogens will still need to examine,on the adverse reaction mechanisms need to be further explored. This paper described the pharmacological effects and mechanism of action of phytoestrogen studies.