中文摘要：

通过3,6-二氯哒嗪与（未）取代芳烷基胺在DMF/NaH或正丁醇体系缩合,合成了13个3-芳甲（乙）氨基-6-氯哒嗪类化合物,其中11个为新化合物,它们的结构均经1H NMR,IR和元素分析确证.初步的生物活性测试结果表明,所合成的化合物对阔叶杂草有一定的抑制作用,如化合物4f在施药量为10μg·mL^-1时对油菜的抑制率是76.42%.讨论了其结构与除草活性的关系.

英文摘要：

A series of 3-arylalkylamino-6-chloropyridazines have been synthesized by the condensation of 3,6-dichloropyridazine with （un）substituted arylalkylamines in N,N-dimethylformamide （DMF） catalyzed by Nail at 120～130℃ or n-BuOH under reflux, and confirmed by IH NMR, IR spectra and elemental analyses. Preliminary bioassay showed that some of them have certain herbicidal activity against broad leaf grasses, for example, at the dosage of 10μg·mL^-1, the inhibition percentage of compound 4f against Brassica napus reached 76.42%. Moreover, the structure-activity relationship was discussed.