中文摘要：

目的应用计算流体力学方法，通过数值模拟技术，分析研究烟雾病术前、术后的血流动力学变化。方法64例缺血型烟雾病及29例出血型烟雾病建立数值模拟的模型，通过软件计算硬脑膜动脉血管融通术（EDAS）术前、术后压力、血流量等血流动力学参数变化。结果缺血型烟雾病术后脑血流量通过手术应用的血管明显增加，出血及缺血病例中颈内动脉末端血管内压力下降（2295．60±758．09）Pa，差异有统计学意义（P〈0.01）。结论EDAS术可以明显地改变颈内动脉的血流及压力情况。

英文摘要：

Objective To analyze and compare the change of hemodynamics between pre and post operation of EDAS on patients of moyamoya disease with the way of computational fluid mechanics. Methods We analyzed the hemodynamicses of 29 hemorrhagic and 64 ischemic patients of moyamoya disease with the way of computational fluid dynamics, and compared the pressure and blood flow between pre and post operation of EDAS on patients of moyamoya disease. Results Calculated with the software of computational fluid dynamic, the pressure of the terminal of internal carotid artery decreased （2295.60 ± 758.09） Pa post operation on hemorrhagic moyamoya disease. There was significant difference（ P 〈 0.01 ） in the pressure and blood flow between pre and post operation. Conclusion The operation of EDAS can effectively improve the blood flow and decrease the pressure of terminal of internal carotid artery.