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中文摘要：
近年来研究发现,高脂饮食（高胆固醇）是阿尔采末病（AD）发病的危险因素之一,高脂饮食能够增加AD的发病率,但胆固醇不能透过血脑屏障进入脑内,所以高脂饮食不能直接导致AD的发生,它是通过何种途径引发AD是许多研究者关注的热点。该文主要围绕高脂饮食引发AD发病的可能机制的研究进展进行了阐述。
英文摘要：
In recent years,it has been found that high fat-diet（high-cholesterol diet） is one of the risky factors for developing Alzheimer＇s disease（AD）,and it can increase the morbidity rate of AD.It is well known that cholesterol can not cross the blood-brain barrier and enter the brain from the blood,which implies that high-fat diet can not directly induce the occurrence of AD.Now,many researchers focus on studying the reasons of AD occurrence induced by high-fat diet.This review reports the current research progress on the possible mechanisms of how the high-fat diet causes AD.
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