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Cembrane Diterpenoids from the Soft Coral Sarcophyton trocheliophorum Marenzeller as a New Class of
ISSN号:0968-0896
期刊名称:Bioorganic & Medicinal Chemistry
时间:2013
页码:5076-5080
相关项目:药物作用新靶标、新机制和新分子实体发现方法与应用研究
作者:
Linfu Liang|Lixin Gao|Jia Li|Orazio Taglialatela-Scafati|Yuewei Guo|
同期刊论文项目
药物作用新靶标、新机制和新分子实体发现方法与应用研究
期刊论文 129
同项目期刊论文
Diastereoselective Michael Reaction of Chiral Nickel(II) Glycinate with Nitroalkenes for Asymmetric
The high affinity of hydroxamate-based MMP-12 inhibitors is due to an inherently slow dissociation o
Identification of Benzofuran-3-yl(phenyl)methanones as Novel SIRT1 Inhibitors: Binding Mode, Inhibit
Structural Switchings Of Staphylococcus Aureus ClpP: A Key To Understanding Protease Mechanism
Identification of N'-(2-oxoindolin-3-ylidene) hydrazide derivatives as c-Met Kinase Inhibitors
The Nature and Magnitude of Specific Halogen Bonds between Iodo-perfluorobenzene and Heterocyclic Sy
Structure and Cytotoxicity of Phidianidines A and B: First Finding of 1,2,4-Oxadiazole System in a M
Palmarumycins BG1-BG7 and Preussomerin BG1: Establishment of Their Absolute Configurations Using The
Lewis Acid-Promoted Highly Diastereoselective Petasis Borono-Mannich Reaction: Efficient Synthesis o
Rhodium-Catalyzed Highly Enantioselective 1,2-Addition of Arylboronic Acids to α-Ketoesters an
Discovering potent inhibitors against c-Met kinase: focused library design, synthesis and bioassay
Highly Diastereoselective Friedel-Crafts Reaction of Arenes with N-tert-Butanesulfinylimino Ester to
Design of Chiral Sulfoxide-Olefins as a New Class of Sulfur-Based Olefin Ligands for Asymmetric Cata
Design of N-Sulfinyl Homoallylic Amines as Novel Sulfinamide-Olefin Hybrid Ligands for Asymmetric Ca
SmI2-Promoted Imino-Reformatsky Reaction for Facile Synthesis of Enantioenriched β-Amino Esters
Conformational transition and energy landscape of ErbB4 activated by neuregulin1β: one microsec
A Theoretical Model for Calculating Voltage Sensitivity of Ion Channels and the Application on Kv1.2
Theoretical and crystallographic data investigations of noncovalent S···O inter
Diterpenes from the Hainan Soft Coral Lobophytum cristatum Tixier-Durivault
Epipolythiodioxopiperazines from Fungi: Chemistry and Bioactivities
Recent advances in the gold-catalyzed additions to C–C multiple bonds
Synthesis of Pyrrolo[1,2-a]quinoxalines via Gold(I)-Mediated Cascade Reactions
Silver- and Gold-Mediated Domino Transformation: A Strategy for SynthesizingBenzo[e]indolo[1,2-a]pyr
Enantioselective Synthesis of Chiral 3-Aryl-1-indanones through Rhodium-Catalyzed Asymmetric Intramo
“Simple Branched Sulfur-Olefins as Chiral Ligands for Rh-Catalyzed Asymmetric Arylation of Cyc
Preparation of α-Alkyl-β-Amino Acids via β-Alanine Ni(II) Complex
Helix unfolding/refolding characterizes the functional dynamics of Staphylococcus aureus Clp proteas
Efficient Synthesis of Optically Active α-Quaternary Amino Acids by Highly Diastereoselective
Design of N-Cinnamyl Sulfinamides as New Sulfur-Containing Olefin Ligands for Asymmetric Catalysis:
Ruthenium(II)-Catalyzed Asymmetric Transfer Hydrogenation Using Unsymmetrical Vicinal Diamine-Based
Paracaseolide A, First r-Alkylbutenolide Dimer with an Unusual Tetraquinane Oxa-Cage Bislactone Skel
9’-Epi-3?,3’?-dimethylxestospongin C, A New Macrocyclic Diamine Alkaloid from the Hainan
Synthesis of 4-Aryl-2(5H)-furanones by Gold(I)-Catalyzed Intramolecular Annulation.
Development of Cell-Active N(6)-Methyladenosine RNA Demethylase FTO Inhibitor
Chiral Sulfinamide-Olefin Ligands: Switchable Selectivity in Rhodium-Catalyzed Asymmetric 1,2-Additi
Absolute Stereochemistry of Integracins A, B and 15'-Dehydroxy-integracin B
Biscembranoids Formed from an α,β-Unsaturated γ-Lactone Ring as a Dienophile: Struc
Design and Synthesis of Polymeric Chiral Bicyclo[3.3.0] Diene as Reusable Ligand for Rhodium-Catalyz
Zn-Mediated Asymmetic Allylation of N-tert-Butanesulfinyl Ketimines: An Efficient and Practical Acce
Lewis Acid-Catalyzed Intramolecular Aza-Friedel-Crafts Reaction of N-tert-Butanesulfinyl Imines: Eff
Rh-catalyzed Enantioselective 1,2-Addition to Unsymmetrical α-Diketones: Tandem One-Pot Synthe
肉芝软珊瑚属中二聚西松烷型二萜化合物的化学和生物活性研究进展
Structure-based computational study of the hydrolysis of New Delhi metallo-beta-lactmase-1.
Asymmetric Michael Addition of N-tert-Butanesulfinyl Imidates: an Efficient Strategy for the Synthes
Highly diastereo- and enantioselective synthesis of syn-β-substituted tryptophans via asymmetri
Discovery of potent small molecule inhibitors of DYRK1A by structure-based virtual screening and bio
The essential role for aromatic cluster in the β3 adrenergic receptor
Assignment of Absolute Configuration of Bis-?-pyrone Polypropionates from Marine Pulmonate Mollusks
Structures and Absolute Stereochemistries of Nortriterpenoids from Schisandra chinensis (Turcz.) Bai
Synthesis and Biological Evaluation of 21-Arylidenepregnenolone Derivatives as Neuroprotective Agent
Phragmalin Limonoids from Chukrasia tabularis var
Disulfide- and Multisulfide-Containing Metabolites from Marine Organisms.
Improved Synthesis of Rupintrivir
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Identification and synthesis of N-(thiophen-2-yI) benzamide derivatives as BRAF(V600E) inhibitors
The stabilization effect of dielectric constant and acidic amino acids on arginine-arginine (Arg-Arg
Discovery and mechanism study of SIRT1 activators that promote the deacetylation of fluorophore-labe
Key targets and relevant inhibitors for the drug discovery of tuberculosis
Dongxiang Liu*. Identification of benzofuran-3-yl(phenyl)methanones as novel SIRT1 inhibitors: bindi
Unprecedented Diterpenoids as a PTP1B Inhibitor from the Hainan Soft Coral Sarcophyton trocheliophor
Virtual Screening and Structure-based discovery Indole Acylguanidines as Potent β-secretase (BA
The specific interaction of the photosensitizer methylene blue with acetylcholinesterase provides a
Asymmetric One-Pot Sequential Mannich/Hydroamination Reaction by Organo- and Gold Catalysts: Synthes
Structure-Based Design, Synthesis of C-1 and C-4 modified analogs of zanamivir as neuraminidase inhi
Design, synthesis, structure-activity relationships, and docking studies of 1-(γ-1,2,3-triazol
Computational drug discovery
Flexibility of the Flap in the Active Site of BACE1 as Revealed by Crystal Structures and MD Simulat
M. Ammonium transport proteins with changes in one of the conserved pore histidines have different p
Rapid and selective access to three distinct sets of indole-based heterocycles from a single set of
Backdoor opening mechanism in acetylcholinesterase based on X-ray crystallography and molecular dyna
Computational Screening for Active Compounds Targeting Protein
Highly diastereoselective synthesis of 3-indolylglycines
Structure and Synthesis of a Unique Isonitrile Lipid Isolated from the Marine Mollusk Actinocyclus p
Cyanobacterial Peptides as a Prototype for the Design of Potent β-Secretase Inhibitors and the
Classification of 5-HT(1A) receptor agonists and antagonists using GA-SVM method
Fragment-based prediction of skin sensitization using recursive partitioning
Structural and functional characterization of the interaction of the photosensitizing probe methylen
Identification of Pentacyclic Triterpenes Derivatives as Potent Inhibitors against Glycogen Phosphor
The gating charge pathway of an epilepsy-associated potassium channel accommodates chemical ligands.
Rhodium-Catalyzed Highly Enantioselective Addition of Arylboronic Acids to Cyclic Aldimines: Practic
Structural modifications of 5,6-dihydroxypyrimidines with anti-HIV activity
Aquantum mechanics/molecular mechanics study on the hydrolysis mechamism of New Delhi metallo-B-lact
Highly Enantioselective of 2-Oxindoles-3-carboxylate Ester to Nitroole?ns Promoted by Cinchona Alkal
Discovery of novel 2-aminopyridine-3-carboxamides as c-Met kinase inhibitors
Discovery of Novel Dual-action Antidiabetic Agents that Inhibit Glycogen Phosphorylase and Activate
Asymmetric total synthesis and identification of tetrahydroprotoberberine
Estimation of Carcinogenicity using Molecular Fragments Tree
Catalytic Mechanism Investigation of Lysine-Specific Demethylase 1 (LSD1): A computational study
Design and Synthesis of Polymeric Chiral Bicyclo[3.3.0] Diene as Reusable Ligand for Rhodium-Catalyzed Asymmetric 1,4-Addition
烷基杂环芳基二硫醚类化合物的合成及抗癌活性研究
Bioactive natural products from Chinese marine flora and fauna