中文摘要：

Ghrelin， 28 氨基酸内脏大脑肽，为它的受体充当内长的 ligand，生长荷尔蒙促泌素受体，行使从生长的刺激的许多功能荷尔蒙分泌物，胃口的规定和精力新陈代谢，和到发炎的调整的房间保护。这评论在 ghrelin 表示和分泌物的规定总结进展。我们介绍 ghrelin 倡导者，在这些过程处理和 ghrelin 先锋，和规定机制的修正的结构。然后，我们讨论发现在 ghrelin 生产的规定重要的因素，包括营养素，荷尔蒙，和自治神经系统。最后，我们在某些生理、病理学的地位在 ghrelin 的水平构画出改变。

英文摘要：

Ghrelin, a 28 amino acid gut brain peptide, acts as an endogenous ligand for its receptor, the growth hormone secretagogue receptor, to exercise a variety of functions ranging from stimulation of growth hormone secretion, regulation of appetite and energy metabolism, and cell protection to modulation of inflammation. This review summarizes the advance in the regulation of ghrelin expression and secretion. We introduce the structure of ghrelin promoter, the processing and modification of ghrelin precursor, and the regulation mechanism in these processes. Then we discuss factors found to be important in the regulation of ghrelin production, including nutrients, hormones, and autonomic nervous system. Finally, we outline the alteration in the level of ghrelin in certain physiological and pathological status.