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HBF4催化末端炔烃水化成甲基酮的合成研究
  • ISSN号：1004-8332
  • 期刊名称：《赣南师范大学学报》
  • 时间：0
  • 分类：O621[理学—有机化学;理学—化学]
  • 作者机构：赣南师范大学化学化工学院,江西赣州341000
  • 相关基金：国家自然科学基金（21202023）;江西省教育厅科技项目（GJJ151005）
作者： 叶东鼐, 傅叶娟, 王青豪, 叶敏
关键词： 甲基酮, 末端炔, 水化, 催化, methyl ketone , terminal alkyne , hydration, catalyzed
中文摘要：

炔烃水化成酮是有机合成中最基本的转化．本论文以四氟硼酸为催化剂，炔烃为反应底物，三氟乙醇（TFE）作溶剂，高效水化合成一系列甲基酮类化合物．考察了不同反应条件，拓展了反应的底物，并提出了反应的可能机理．

英文摘要：

Converting alkynes into carbonyl compounds through hydration is a fundmental transformation in organic synthesis. An efficient HBF4-catalyzed hydration of terminal alkynes to synthesis of methyl ketones has been developed. Trifluoroethanol was used as solvent. We also optimized the reaction conditions, examined the scope of the substrates and proposed the possible mechanisms.

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期刊信息
  • 《赣南师范大学学报》
  • 主管单位:赣南师范大学
  • 主办单位:赣南师范大学
  • 主编：孙宏安
  • 地址：江西赣州经济技术开发区赣南师院黄金校区
  • 邮编：341000
  • 邮箱：gnsyxb@vip.126.com
  • 电话：0797-8393677
  • 国际标准刊号：ISSN：1004-8332
  • 国内统一刊号：ISSN：36-1346/C
  • 邮发代号:
  • 获奖情况:
  • 首届全国优秀社科学报
  • 国内外数据库收录:
  • 被引量:3