牛传染性鼻气管炎(Infectious bovine rhinotracheitis,IBR)是由牛疱疹病毒I型(Bovine herpes virus-1,BHV-1)引起的牛的一种急性、热性、接触性传染病.该病毒的危害性在于病毒侵入牛机体后,潜伏在一些特定的部位,致使病毒持续性感染,病牛长期甚至终身带毒,给控制和消灭本病带来很大困难,给全球养牛业造成了重大经济损失.文章就BHV-1分子生物学、诊断及各类疫苗进行阐述,旨在为该病的进一步研究提供理论参考.
Infectious bovine rhinotracheitis(IBR),caused by Bovine herpes virus-1,was an acute,thermal and contagious infectious diseases.The dangers of the viruses lurked in the certain special locations,resulted in persistent infection for a long-term or even a lifelong infection in cows after the virus invaded the body of cattle.The control and eradication of the disease had many difficulties,which caused the significant economic losses in the cattle industry over world.This article reviewed the BHV-1 molecular biology,diagnosis and various vaccines.It aimed at providing the theoretical reference of further research diseases.