中文摘要：

在获得表面修饰氨基官能团的磁纳米棒,为进一步偶联生物分子制备出磁生物双靶向纳米药物奠定基础。以部分氧化法制备了磁性FeO（OH）纳米棒,并在保持原有形貌的基础上对其进行硅胶包覆和氨基功能化,从而获得功能化磁纳米药物载体。磁纳米棒的形貌特征、晶体结构、磁性质和表面基团分别通过TEM（SAED）、XRD、VSM和FTIR进行表征。结果表明,具有软磁性的正交晶系单晶FeO（OH）纳米棒直径介于30～70nm间,平均长径比为37,硅胶包覆层厚度为45nm;在FeO（OH）纳米棒外面包覆上硅胶后,除矫顽力变化不明显外,其饱和磁化强度和剩余磁化强度均有所下降;3380～3200cm-1（ν-NH,伸缩振动）和1650～1510cm-1（δ-NH,变形振动）分别是—NH2的两个特征红外吸收带,说明磁性FeO（OH）纳米棒表面具有氨基官能团。

英文摘要：

This paper aims to obtain amino-modified magnetic nano-rods as drug-carriers,for further coupling with biological molecules to prepare magnetic biological dual target nano-drugs.Magnetic FeO（OH） nanorods were prepared by method of partial oxidation.Based on maintaining the original morphologies,the products were coated by silica and modified by amino group for synthesizing nano-drugs carriers.The crystal morphology,structure,magnetism and surface group of products are characterized by TEM（SAED）,XRD,VSM and FT-IR,respectively.The results show that the size of orthorhombic FeO（OH） nanorods with soft magnetism is between 30 and 70nm,and average aspect ratio is about 37.Thickness of silica-coated FeO（OH） nanorods is about 45nm.After FeO（OH） nanorods were coated with silica gel,the saturation magnetization and residual magnetization are decreased,except for no obvious change of the coercivity.The infrared absorption bands of —NH2 appeared around 3380-3200 and 1650-1510cm-1 demonstrate the amino group on the surface of the products.