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中文摘要：
地中海饮食，特别是橄榄油，赋予了地中海周边国家人民对于退行性疾病的强力抵抗，尤其是心血管疾病和肿瘤的发生率以及致死率相对更低。羟基酪醇是橄榄油中的多酚类化合物之一，在防治紫外辐射、糖尿病、老年性视网膜黄斑病变、心血管疾病以及肿瘤等方面都具有重要的生物学效应。将具体阐述羟基酪醇作为一种线粒体营养素（如通过调节线粒体的动态变化以及Nrf2介导的抗氧化酶的诱导等）如何促进其有益功能。
英文摘要：
Mediterranean diets, especially olive oil, play a vital role in resistance to degenerative diseases, particularly cardiovascular diseases and cancer, promoting a relatively lower incidence and mortality. As one of polyphenolic compounds in olive oil, hydroxytyrosol exhibits excellent biological effects on resistance to many diseases, such as UV radiation, diabetes, age-related macular disease, cardiovascular disease, and cancer, etc. This review will focus on the regulation mechanism of hydroxytyrosol as a mitochondrial nutrient through promoting mitochondrial dynamics and Nrf2-mediated antioxidant and detoxifying enzymes induction.
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