目的:在社区开展中医综合方案干预绝经后骨质疏松症(PMOP)的示范性研究。方法:采用前瞻性类试验设计,纳入病例40例,分两组,每组20例。试验组用中医综合干预方案,对照组口服钙制剂,疗程均6个月;观测指标为视觉模拟疼痛评分(VAS)、中医症状积分及骨矿密度值(BMD);运用发展模型进行疗效评价研究。结果:试验组与对照组相比,VAS的平均结局分值下降(P〈0.05);两组对下肢拘挛、畏寒肢冷、骨痛、腰膝酸软症状均有一定的缓解作用,且试验组更优于对照组(P〈0.05)。对于减缓腰椎BMD的下降试验组优于对照组(P〈0.05)。结论:中医综合干预方案对缓解患者疼痛、改善症状优于单一钙剂,对延缓BMD的下降也有一定的作用。
Objective: Carrying out a demonstration study of postmenopausal osteoporosis with integrated project in TCM in the community.Methods: A prospective test design was used,and 40 cases was selected to divide into the two groups.The VAS,the changes of TCM syndromes and BMD were observed in both groups.Exploratorying the research on clinical effectiveness evaluation of PMOP with integrated project in TCM based on the growth model.Results: VAS scores of the experimental group were decreased significantly compared with control group(P0.05);TCM syndromes scores of the experimental group were decreased significantly compared with control group(P0.05).For the slow decline in BMD,experimental group was better than the control group with statistical difference(P0.05).Conclusion: The traditional integrated project can relieve the pain and the symptoms.There is a certain effect on slowing down the decline of bone mineral density.