目的本研究通过对抑郁症相关性失眠和抑郁症不伴失眠两组患者进行中医证候要素观察,探索抑郁症相关性失眠患者证候要素分布规律及特点,并分析抑郁症相关性失眠患者证候要素与失眠形式之间的关系。方法本实验共纳入符合标准的抑郁症相关性失眠组患者100例和抑郁症不伴失眠患者50例,自拟中医证候要素观察表,对两组患者临床症状进行观察,比较两组患者证候要素特点,统计抑郁症相关性失眠患者失眠形式特点,并进一步观察抑郁症相关性失眠患者证候要素与失眠形式间是否存相关性。结果研究结果表明,抑郁症相关性失眠患者中主要的中医证候要素依次为"气虚"、"气滞"、"火热"、"阴虚"、"血虚"、"痰证"(发生均大于50%)。两组患者在中医证候要素"阴虚"对比时存在明显差异(P〈0.01)。经相关性检验提示抑郁症相关性失眠患者中医证候要素"气虚"与"早醒"呈显著正相关性(P〈0.01)。结论抑郁症相关性失眠的患者较其他抑郁症患者存在明显的"阴虚"表现。抑郁症相关性失眠中医证候要素"气虚"与失眠形式中早醒表现相关。
Objective The study mainly observes the distribution law on syndrome elements of patients with depressive insomnia by statistic elements of Traditional Chinese Medicine ( TCM) syndrome in the group on depressive insomnia and the group on depression without insomnia. Then it analyzes the relationship between patients with depressive insomnia and the types of insomnia. Methods This experiment included 100 patients with depressive insomnia and 50 patients with non-insomnia depression. To test all patients with self-observation to be elements of TCM syndrome observed information table,clinical symptoms in two groups of patients were observed. Compared elements of TCM syndrome between two groups. Then it statistics types features of insomnia of the patients with depressive insomnia. And further it observed whether or not exists a correlation between elements of TCM syndrome and types features of insomnia of the patients with depressive insomnia. Results The results show that the major elements of TCM syndrome in depressive insomnia patients in order to"Qi deficiency","Qi stagnation","Fire syndrome","Yin deficiency","Xue deficiency","Phlegm syndrome"( Probability 50% ) . Between the two groups,the "Yin deficiency"shows significantly different when comparing ( P〈0. 01) . The Spearman correlation test shows that"Qi deficiency"and the insomnia in the end of sleep ( early waking) are significantly positively correlated ( P〈0. 01) . Conclusion The patients with depressive insomnia have obvious "Yin deficiency"than the other depressive patients. The"Qi deficiency"maybe has important relationship with insomnia symptoms in the early awakening among the patients with depressive insomnia.