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疏肝泻火养血安神法干预失眠症的临床研究
  • ISSN号:1674-1749
  • 期刊名称:环球中医药
  • 时间:2013
  • 页码:500-504
  • 分类:R256.23[医药卫生—中医内科学;医药卫生—中医学]
  • 作者机构:[1]北京中医药大学东方医院脑病二科,100078
  • 相关基金:国家自然科学基金(81072717)
  • 相关项目:基于肝郁脾湿病机研究抑郁症学习记忆障碍大鼠的海马cAMP-PKA-CREB-BDNF通路表达及中药干预效应
作者: 郭蓉娟|
中文摘要:

目的探索疏肝泻火养血安神法治疗失眠症的临床疗。方法选取门诊失眠患者30例,采用前后对照法,以疏肝泻火养血安神法干预1个月,采用配对t检验方法对干预前后的匹兹堡睡眠质量指数(PSQI)、汉密顿焦虑量表(HAMA)、汉密顿抑郁量表(HAMD)、临床记忆测查、威斯康星卡片分类(WCST)和中医肝火量表的分值进行统计评定。结果疏肝泻火养血安神法治疗肝郁化火型失眠症有效率93.33%;该法干预前后匹兹堡睡眠质量指数、汉密顿焦虑量表、汉密顿抑郁量表分值下降;记忆商低于正常的失眠症患者的记忆商、联想学习及人物特点回忆三方面均有提高;威斯康星卡片分类分值前后无明显差异;中医症状在总分、急躁易怒、胸闷和胁痛等症状分值上有下降;非线性脑电图分析发现在记忆任务下左额叶、左中央、左枕叶、左中颞和左后颞5个导联干预前后有差异有统计学意义。结论疏肝泻火养血安神法治疗肝郁化火型失眠症有效;该法对睡眠质量、情绪状况和中医肝郁化火主要症状改善明显;对记忆损害有一定程度的改善;对左侧优势半球尤其是颞叶的神经细胞功能的复杂度有提高。

英文摘要:

Objective To explore Shugan Xiehuo Yangxue Anshen of the clinical effect of treat- ment of insomnia. Methods 30 cases of patients with insomnia clinic, a law Shugan Xiehuo Yangxue Anshen treatment, a course of treatment, the selection of the Pittsburgh Sleep Quality Index (PSQI), Hamilton Anxiety Scale (HAMA) , the Hamilton Depression Rating Scale ( HAMD ), the memory of Investigation, the Wisconsin Card Sorting (WCST) and the Chinese hepatitis Scale respectively, a comprehensive evaluation of its efficacy. Results The effective rate of Shugan Xiehuo Yangxue Anshen treatment of Ganyn huahuoxing insomnia 93.33% ; this method before and after the intervention, the Pittsburgh sleep quality index, Hamilton Anxiety Scale, Hamilton Depression Scale scores decreased; memory quotient was lower than normal in patients with insomnia, memory quotient association characteristics of learning and memory in three aspects are improved; and the Wisconsin Card Sorting no significant differences in scores of TCM symptoms decreased; in the total score, irritability, chest and hypochondrium pain and other symptoms scores; nonlinear EEG analysis found in memory tasks in left frontal lobe, the left central, left occipital lobe, left Zhongnie and left posterior temporal before and after the 5 lead intervention had significant difference. Conclusion Shugan Xiehuo Yangxue Anshen treatment of Ganyu huahuoxing insomnia effectively ; the law of the main symptoms of sleep quality, mood status and TCM liver depression of the fire was improved obviously; there is a certain degree of improvement of memory impairment; on the left dominant hemisphere especially nerve cell function temporal complexity increase.

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期刊信息
  • 《环球中医药》
  • 中国科技核心期刊
  • 主管单位:中华人民共和国卫生部
  • 主办单位:中华国际医学交流基金会
  • 主编:张伯礼
  • 地址:北京东城区东四西大街46号综合楼203
  • 邮编:100711
  • 邮箱:hqzhyy@163.com
  • 电话:010-65269860
  • 国际标准刊号:ISSN:1674-1749
  • 国内统一刊号:ISSN:11-5652/R
  • 邮发代号:80-726
  • 获奖情况:
  • 中国科技核心期刊
  • 国内外数据库收录:
  • 美国化学文摘(网络版),美国剑桥科学文摘,中国中国科技核心期刊
  • 被引量:7690