目的:研究近日节律的改变与高血压脑出血手术治疗预后的关系。方法:收集100例高血压基底节区脑出血的病例,每例患者均进行了标准的开颅血肿清除术。术后连续24小时监测心率,每小时记录一次。用单一余弦法进行术后24小时心率的近日节律分析。根据术后近日节律的出现和消失将患者分组,利用统计学比较两组预后的差异。结果:术后24小时心率近日节律出现组预后好的患者比例明显优于消失组(P〈0.01)。结论:近日节律的改变有可能早期预测高血压脑出血手术治疗的预后。
Objective: Study of the relationship between change in circadian rhythm and postoperative prognosis from hypertensive intracerebral hemorrhage. Method: 100 cases of hypertensive intracerebral hemorrhage at basal ganglia had been collected, which ev- ery case was performed operation to remove hemotoma by standard craniotomy. Value of Heart Rate (HR) was recorded by monitor every 1 hour for 24 hours after operation. Circadian rhythm of the first 24-hour was analyzed by single Cosinor. 100 cases were divid- ed into two groups by appearance and disappearance of circadian rhythm after operation. The difference was compared by statistics.. Result: Percentage of good prognosis in appearance of circadian rhythm group was better than disappearance of circadian rhythm group (p〈~0. 01). Conclusion: Change of circadian rhythm would be an early predictor of postoperative prognosis from hypertensive intracerebral hemorrhage.