中文摘要：

目的：探讨合并颈动脉粥样硬化（CAS）的原发性高血压（EH）患者血压近日节律的特征，及与腔隙性脑梗死（CLI）的关系。方法：高血压患者114名，以彩色多普勒检测患者的颈动脉内膜情况及动态血压仪监测患者24小时血压变化，分为CAS组与CAN（颈动脉正常）组，以差值百分比法分析24小时血压节律变化情况，并进行统计学分析。结果：在CAS组的EH患者中，夜间收缩压和舒张压下降率明显低于CAN组患者（P〈O．05），发生血压近日节律紊乱的患者明显多于CAN组（P〈O．05）。结论：CAS的发生与EH患者血压近日节律的紊乱有密切关系，是缺血性脑卒中发生的危险因素。

英文摘要：

Objective： To explore the feature of circadian rhythm of the patients with carotid artery atherosclerosis（CAS）, and the relation of cerebral infarction in the patients of essential hypertension（EH）. Methods： Used color-doppler ultrasonic equipment and ambulatory blood pressure monitor to investigate the changes of carotid artery intima and ambulatory blood pressure in 114 hyperten- sives. Patients were divided in CAS group and carotid artery normal（CAN） group. Statistics analysis was conducted. Results： In merges in the CAS EH patient, at night the systolic pressure and the diastolic pressure descending rate are obviously lower than the CAN EH patient, has the blood pressure day and night rhythm disorder patient to be more than the CAN group obviously. Conclusions： The findings suggest that occur of CAS in EH patients have accompanies with the change of circadian rhythm. CAS is an important risk factor in the onset of ischemie infarct.