中文摘要：

蛋白质酪氨酸硝化是一氧化氮依赖的氧化应激的生物标志。蛋白质硝化将会直接影响蛋白质的催化活性、细胞信号传递和细胞骨架结构，导致相关病症的发生发展。本文介绍了铁在不同酪氨酸硝化途径中的作用，结果提示体内的微量铁对蛋白质硝化起着重要作用。

英文摘要：

biomarker of NO-dependent oxidative stress. Protein nitration will induce the changes of protein catalytic activities, cell signaling and cell skeletal structure, and lead to relevant pathological events. In this paper, the roles of iron in different pathways of protein nitration are introduced, and the results indicated that microelement iron in vivo plays an important role in protein nitration.