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中文摘要：
Ghrelin是生长激素促分泌素受体（growth hormone secretagogue receptor,GHSR）的内源性配体,在大鼠胃组织中首次被发现,通过与其特异性受体结合发挥生物学作用。近年来随着对其研究的深入,发现Ghrelin在多种组织中合成分泌,不仅在消化、内分泌等系统产生重要作用,对脑功能也有很大影响,可提高学习记忆能力、影响睡眠、与应激焦虑关系密切并且对脑神经起保护作用。本文总结近几年的文章,旨在通过对Ghrelin对脑功能影响的介绍,为以后的相关研究奠定基础。
英文摘要：
Ghrelin is the endogenic ligand of growth hormone secretagogue receptor（GHSR）,which was firstly detected in stomach of mouse and played a role in combing with specificity receptor.Research in recent years showed that Ghrelin was synthesised and secreted in many tissues.Besides the influence on digestive system and endocrine system,it can also effect on brain function,such as increasing learning abilities,influencing on sleep quality and emotion,protecting the cranial nerves.The article summarizes many papers published in recent years in order to lay the foundation of correlational investigation through the introduction of influence on brain function of Ghrelin.
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