中文摘要：

目的探讨辅助性T细胞9（Th9）在变应性鼻炎小鼠鼻黏膜中的表达及意义。方法构建以卵清蛋白致敏的Balb/c小鼠变应性鼻炎模型作为实验组,同期使用生理盐水作为对照组。取2组小鼠鼻黏膜组织,使用流式细胞仪检测2组小鼠鼻黏膜中Th9细胞比例。结果 2组小鼠鼻黏膜中均有Th9细胞的存在,并且实验组中Th9的比例高于对照组[（1.265%±0.381%）vs（0.616%±0.041%）],差异具有统计学意义（P〈0.05）。结论首次明确变应性鼻炎鼻黏膜中Th9细胞的比例,为阐明AR的发病机制提供了新的理论依据。

英文摘要：

This study designed to investigate the expression and significance of helper T cell 9（Th9） in nasal mucosa of allergic rhinitis mice.Balb/c mouse allergic rhinitis model was constructed with ovalbumin sensitization as the experimental group,and saline was used for control group.Flow cytometry was employed to detect Th9 cells proportion in nasal mucosa of the two groups.Data showed that Th9 cells exist in both the two groups.Th9 proportion in experimental group was higher than that in control group[（1.265%＋0.381%） vs（0.616%＋0.041%）],and the difference was statistically significant（P〈0.05）.In conclusion,this study confirms Th9 cells proportion in nasal mucosa of allergic rhinitis,which provides a new theoretical basis for elucidating the pathogenesis of allergic rhinitis.