中文摘要：

作为介绍房间的职业抗原，树枝状的房间(DC ) 极大地决定天生、适应的免疫的质量。因此，基于 DC 的免疫疗法是在最近的年里的癌症免疫疗法的热点之一。尽管这唯一的治疗学的策略被美国食物药品管理局为前列腺癌症治疗同意了，基于 DC 的免疫疗法的功效尚待进一步被改善。而且，它仍然不关于 DC 的免疫学的基础是完全清楚的，它是为基于 DC 的免疫疗法的进步的另一个障碍。由于他们的唯一的物理化学的性质， nanomaterials 证明了在上面探讨这些的潜力提及问题并且为优化基于 DC 的免疫疗法提供了重要指南。然而，它仍然在为这块新兴的地的开始的阶段，在要回答的这治疗学的策略的合理设计有许多批评问题。因此，它是极大地必要在这块地里考察并且分析最近的进步。在这评论，我们主要为基于 DC 的免疫疗法集中于各种各样的类型 nanoparticles 的发展。这块地里的存在挑战也被讨论。

英文摘要：

As professional antigen presenting cells, den- dritic cells （DCs） greatly determine the quality of the innate and adaptive immunities. Therefore, DC-based immunotherapy has been one of the hotspots in cancer immunotherapy in recent years. Although this unique therapeutic strategy has been approved by U.S. Food and Drug Administration for prostate cancer treatment, the efficacy of DC-based immunotherapy remains to be further improved. Moreover, it is still not completely clear about the immunological basis of DCs, which is another hurdle for the progress of DC-based immunotherapy. Due to their unique physicochemical properties, nanomaterials have shown potentials in addressing these above mentioned problems and have provided important guidelines for optimizing DC-based immunotherapy. However, it is still at the starting stage for this emerging field and there are many critical questions in the rational design of this ther- apeutic strategy to be answered. Therefore, it is greatly necessary to review and analyze recent progresses in this field. In this review, we mainly focus on the development of various types nanoparticles for DC-based immunother- apy. The existed challenges in this field are also discussed.