中文摘要：

首先通过化学沉淀法制备磁性氧化铁羟基磷灰石（Fe1O4／HA），然后以壳聚糖（CS）为基体，利用原位沉析法将Fe3O4／HA与CS复合，制得磁性Fe3O4／HA／CS复合材料．经XRD、粒径分布和PPMS测试，结果表明了飓04／HA复合物的生成．系统研究了磁性Fe3O4／HA／CS棒材力学性能的影响因素，最终确定Fe3O4与HA质量比为3：17，磁性Fe3O4／HA与CS质量比为9：91时，棒材的力学性能最优，弯曲强度可达到87．0MPa，弯曲模量1．57GPa．

英文摘要：

Chitosan （CS） is suggested for using in orthopedic applications to provide temporary mechanical support for the regeneration of bone cell ingrowth due to its good biocompatible, non-toxic, biodegradable, and inherent wound healing characteristics. In the present study magnetic iron oxide/hydroxyapatite （HA）/chitosan rods were prepared by blending magnetic iron oxide/hydroxyapatite with chitosan via in situ precipitation. Magnetic iron oxide/ hydroxyapatite was obtained by co-precipitation method. X-ray diffraction （XRD）, size distribution and magnetic measurements were performed to characterize the as-prepared magnetic iron oxide/hydroxyapatite, the results confirmed the formation of magnetic iron oxide/hydroxyapatite with particle size of around 1380 nm, and its saturated magnetic intensity （M~） was about 33.3 emu. When the total inorganic and CS content kept constant, effect of the ratio of magnetic iron oxide and hydroxyapatite on the mechanical properties was invested, the reuhs showed that the best ratio of magnetic iron oxide and hydroxyapatite was 3 ： 17, and the effect of the ratio of magnetic iron oxide/HA and chitosan on the mechanical properties was also investigated, 9：91 was the best ratio. It could be also concluded from the three point bending test that the mechanical properties improved as the inorganic content decreased. Bending strength and bending modulus of the magnetic iron oxide/HA/CS composite were 87.0 MPa and 1.57 GPa, respectively. The mechanical properties of magnetic iron oxide/HA/CS composites were stronge while compared to those of human bones, due to the special performances of magnetic iron oxide and hydroxyapatite, this composite could have potential use in bone repair domain. The microstructure studies of magnetic iron oxide/hydroxyapatite/ chitosan rods were carried out by scanning electron microscopy （SEM）, and SEM micrographs supported the results of the three point bending test.