中文摘要：

以阿散酸为虚拟模板分子,2-乙烯吡啶为功能单体,乙二醇二甲基丙烯酸酯为交联剂,合成了对洛克沙胂具有高选择性的分子印迹聚合物。通过考察致孔剂、单体及交联剂等因素对合成聚合物性能的影响,获得优化聚合配方为：阿散酸、2-乙烯吡啶、乙二醇二甲基丙烯酸酯、甲醇-乙腈（1∶1,V/V）及偶氮二异丁腈之比为1 mmol∶4 mmol∶20 mmol∶6 mL∶60 mg。合成印迹聚合物对洛克沙胂的最大吸附量为0.93 mg/g,作为固相萃取填料分离、富集洛克沙胂的优化萃取条件为：水和乙腈活化平衡,乙腈上样,水和甲醇依次淋洗,5%甲酸甲醇溶液洗脱。洛克沙胂在分子印迹固相萃取柱上的回收率达到95%以上,而非分子印迹固相萃取柱的回收率仅为43.1%。制备小柱应用于池塘水中洛克沙胂的净化富集,检测限可达0.05 mg/L。

英文摘要：

Molecularly imprinted polymers（MIP） with high selectivity to roxarsone（ROX） were prepared using arsanilic acid（ASA） as dummy template,2-Vinylpyridine（2-VP） as monomer,ethylene glycol dimethacrylate（EGDMA） as cross-linker.The effects of porogen,monomer and cross-linker on the recognition capability of MIP were investigated.The optimal ratio of ASA,2-VP,EGDMA,methanol-acetonitrile（1 ∶ 1,V/V） and azobisisobutyronitrile was 1 mmol ∶ 4 mmol ∶ 20 mmol ∶ 6 mL ∶ 60 mg,respectively.The maximum adsorption of MIP to ROX was 0.93 mg/g.The optimal conditions of solid phase extraction of MIP as adsorptive material for selective extraction and enrichment of ROX were： conditioning with water and acetonitrile,loading ROX in acetonitrile,washing with water and methanol,and eluting with methanol-formic acid（95 ∶ 5,V/V）.The recovery of ROX on MIP cartridge was above 95% and that on NIP cartridge was only 43.1%.The prepared MIP cartridge was applied to extract and enrich ROX in pond water,and the limit of detection of ROX was 0.05 mg/L.