中文摘要：

神经系统的功能在很大程度上取决于神经元-神经胶质细胞间的信息交流。而神经元与神经胶质细胞间复杂的信号通路间的相互作用涉及多种信号分子,嘌呤和嘌呤受体在此过程中起着重要作用。长久以来,关于中枢神经系统的研究主要集中在神经元,相比之下神经胶质细胞主要被作为支持细胞或在应对脑损伤时提供导向作用。最新研究表明,神经胶质细胞在神经系统疾病的发生发展中也扮演着重要角色。该文主要阐述嘌呤受体在神经元和神经胶质细胞之间的相互作用及其在神经系统疾病中的作用。

英文摘要：

The function of the nervous system is largely determined by the communication between neurons and glial cells.The interaction of complex signaling pathways between neurons and glial cells involves in a variety of signaling molecules.Purines and the purinergic receptors play a crucial role in the process of the interaction.For a long time,the study on the central nervous system is mainly focused on neurons,while glial cells are mainly used as support cells or in response to brain injury to provide a guiding role.The latest research shows that glial cells play an important role in the occurrence and development of nervous system diseases.We will summarize the function of purinergic receptors in the interaction of neurons and glial cells and in neurological diseases.