将来自南海红树林内生真菌E33和K38的共培养,从该培养液提取物中分离到Castaneiolide(1),脑苷脂-1-O-吡喃葡萄糖基- (2S, 3R, 4E, 2′R ) -2-N-(2′-羟基棕榈酰) -9-甲基- 4, 8-sphingadienine (2),3β,7β,19-三羟基-5-烯-胆甾烷(3),3-羟基-4-(3-甲基-2-丁烯氧) 基-苯甲醛 (4),对羟基苯甲醛(5)五个代谢产物,其中化合物1,2,4为首次从海洋真菌里得到。化合物1,2,3,4以往未从单独发酵的两菌中分离得到。
Two mangrove endophytic fungi K38 and E33 from the South China Sea Coast were co-clutured. Five secondary metabolites, including Castaneiolide(1),(2S, 3R, 4E,2′R)-2-N-(2′-hydroxy-palmitoyl )-1-O-β-D-gluco-pyranosyl-9-methyl-4, 8-sphingadienine(2), cholesta -5-en-3β,7β,19α-triol(3),3-hydroxy-4-(3-methylbut-2-enyloxy)benzaldehyde (4),4-hydroxybenzaldehyde(5), were isolated from this crude extracts. Among them, compounds 1,2,4 were found in marine fungi for the first time, and compounds 1,2,3,4 were not obtained from these two strains by pure fermentation.