中文摘要：

目的：调查不同证型胃食管反流病（gastroesophageal reflux disease,GERD）患者的生活质量,为GERD的个体化治疗提供依据。方法：运用SF-36量表对武警后勤学院附属医院的消化内科260例GERD患者进行生活质量调查,另外260例健康者作为对照。分析健患之间,患者不同中医证型之间生活质量的差异。所有资料采用Microsoft Excel建立数据库,使用SPSS 17.0统计软件进行数据分析。根据数据的分布特征,分别采用频数分布表、t检验及单因素方差分析。结果：肝胃郁热证患者最多。病例组7个纬度生活质量评分均明显低于健康对照组,差异有统计学意义（P〈0.05）。不同中医证型的GERD患者,在生理功能（PF）、生理职能（RP）、总体健康（GH）和精神健康（MH）四个维度,得分总体均数差异有统计学意义（P〈0.05）;余四个维度差异均无统计学意义（P〉0.05）。结论：GERD患者的生活质量比正常健康人明显下降,精神心理异常对GERD患者生活质量的影响较大。不同证型患者生活质量下降的维度不同,临床医师在治疗中必要时予其个体化健康教育宣教以提高其生活质量。

英文摘要：

Objective： To investigate the patients＇ life quality of different TCM syndrome types of gastroesophageal reflux disease（ GERD） and provide the basis for individualized treatment of GERD. Methods： To investigate the quality of life of 260 patients with GERD by the SF-36 scale,which from digestive internal medicine in Armed Police Logistics College Affiliated Hospital,another 260 healthy ones as control. And then we analyzed the differences of life quality between patients and healthy from Affiliated Hospital of Logistics University of People＇s Armed Police Force. The survey data was used to create a database with Microsoft Excel. Statistical analysis was performed by using the SPSS 17. 0 software package. According to the distribution of the data,we would adopt the frequency distribution table,T test and One-Way ANOVA to analyze the statistics. Results： The life quality scores of GERD cases were significantly lower than that of healthy controls in 7 dimensions and the difference was statistically significant in the rest dimensions（ P 〈0. 05）. The overall mean score was significantly different（ P 〈0. 05） in the physiological function（ PF）,physiological function（ RP）,GH and MH dimensions,which was in different TCM syndrome types of patients with GERD. No significant differences were observed in the other 4 dimensions（ P 〈0. 05）. Conclusion： The life quality of patients with GERD was obviously lower than that of the healthy. Psychology abnormality had influence on the quality of life in patients with GERD. Different syndrome types in patients decline in different dimensions of life quality. So clinicians should give individualized health education when it is necessary in order to improve their quality of life.