为了深入研究心血管系统的生理机制以及探讨心血管系统的血流动力学参数与心血管疾病之间的关系,文中基于流体力学与电气网络的相关基础理论,根据人体心血管循环系统的解剖模型,提出一种基于集总参数的由体循环、肺循环和心脏组成的心血管系统仿真模型。重点分析了体循环子模型,并利用MATLAB 工具进行数学仿真,得出正常生理状况下的心血管参数,给出收缩压、舒张压、心室血容量等血流动力学参数。根据临床诊断参数调整体循环模型的各个参数,利用计算机仿真出高血压和心衰状况下的血流动力学仿真结果。仿真结果与临床的症状相一致,证明文中提出的模型具有一定的可行性。
In order to study the physiological mechanism of cardiovascular system in depth,and discuss the relationship between the hemo-dynamic parameters of cardiovascular system and cardiovascular disease,a lumped-parameter human cardiovascular circulation system has been put forward based on the relative basic theories of fluid mechanics and electrical network,which is divided into three parts:systemic circulation,pulmonary circulation,and the heart model. The systemic sub models has been emphatically analyzed and the mathematical simulation has been conducted by MATLAB to obtain cardiovascular parameters of the normal physiological conditions,giving the ven-tricular hemodynamic parameters such as systolic pressure,diastolic pressure,blood capacity. According to the clinical diagnosis to adjust each parameter of systemic model,use the computer to simulate the blood flow dynamics simulation results under the conditions of hyper-tension and heart failure. The simulation result is consistent with the clinical symptoms,which verifies the feasibility of the model.