采用计算机辅助设计技术设计多孔材料的结构。用离心灌注法将高固相含量的β-磷酸三钙(β-tricalciumphosphate,β-TCP)浆体注入多孔模具,通过改性淀粉原位凝固技术制备陶瓷坯体,最后高温烧结去除有机成分,得到β-TCP的多孔陶瓷。探讨分散剂加入量对浆料流变性能的影响,并对多孔支架材料的物相组成和显微结构进行分析。结果表明:采用该方法可以制备具有可控孔隙结构的β-TCP多孔陶瓷,这种多孔陶瓷是一种比较理想的骨组织工程支架材料。
The computer aided design(CAD) was adopted to design microstructure of porous materials.The rapid prototyping technique was used to prepare a polymer mold of the porous materials,and then the mold was filled with high concentration β-tricalcium phosphate slurry using the centrifugal perfusion method.A gel network was formed by the swelling and gelation of the modified starch.The sample was sintered at high temperature and the polymer mold and starch were clean-burned,and then a β-tricalcium phosphate porous scaffold was obtained.Effects of technological parameters,such as concentration of dispersant and modified starch content on rheological property of β-tricalcium phosphate slurry were studied,and crystal composition and microstructure of porous scaffolds were investigated.The results indicate that β-tricalcium phosphate ceramics with controllable porous architecture are obtained by the in-situ consolidation methods.This porous ceramic can be used as a tissue engineering scaffold.